Optogenetic tools for cell biological applications
نویسندگان
چکیده
منابع مشابه
Optogenetic tools for in vivo applications in neonatal mice
Spontaneous neural activities exist early in development and their spatiotemporal patterns play important roles in the development of sensory maps such as maps of retinotopy in the visual system. We summarized different optogenetic tools, including transgenic mouse lines, viral-mediated transfection and electroporation methods to enable the expression of light-gated channelrhodopsin (ChR2) in r...
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The capture and utilization of light is an exquisitely evolved process. The single-component microbial opsins, although more limited than multicomponent cascades in processing, display unparalleled compactness and speed. Recent advances in understanding microbial opsins have been driven by molecular engineering for optogenetics and by comparative genomics. Here we provide a Primer on these ligh...
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This mini-symposium aims to provide an integrated perspective on recent developments in optogenetics. Research in this emerging field combines optical methods with targeted expression of genetically encoded, protein-based probes to achieve experimental manipulation and measurement of neural systems with superior temporal and spatial resolution. The essential components of the optogenetic toolbo...
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Photosensory receptors have been in the center of vision research and photobiology since the discovery of rhodopsin in 1876 by Franz Boll. However, in the last 10 years the rise of optogenetics has placed them in a broader focus. The majority of these biological light-sensors consist of a protein/pigment complex that alters the activity of a cognate biological effector upon absorption of a phot...
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ژورنال
عنوان ژورنال: Journal of Thoracic Disease
سال: 2017
ISSN: 2072-1439,2077-6624
DOI: 10.21037/jtd.2017.11.73